See how PGY-1 interns and PGY-2 residents built clinical confidence during orientation with DDx.
Overview
At UC Irvine's Emergency Medicine Residency Program, faculty sought to give incoming residents a structured and interactive primer to prepare them for clinical encounters and rotations. The goal was threefold: reinforce foundational knowledge, uncover early learning gaps, and offer remediation tools for residents who might need extra support. As part of intern orientation in July, UC Irvine piloted DDx with 13 residents — 9 PGY-1 interns and 4 PGY-2 residents — who completed five residency-level DDx cases over two weeks.
Overview
The challenge
The residency program sought a scalable case-based learning solution that would allow incoming residents to practice clinical reasoning and diagnostic decision-making through realistic patient encounters while preparing them for their first shifts in the emergency department.
As new physicians step into their clinical roles, early support in diagnostic reasoning and clinical decision-making can profoundly impact confidence and performance. Faculty at UC Irvine recognized the need to provide incoming residents with a structured and interactive primer — one that could reinforce foundational knowledge, identify gaps early, and offer remediation tools for residents who might need extra support — all before they began seeing real patients in the emergency department.
The solution
Deployed 5 residency-level DDx cases during intern orientation over two weeks; 9 PGY-1 interns and 4 PGY-2 residents completed cases individually at their own pace; Cases selected to reflect core challenges of emergency medicine and simulate real clinical encounters; Residents practiced history-taking, test ordering, diagnostic reasoning, and clinical management with immediate feedback at each step
The inclusion of DDx during residency orientation proved to be seamless and well-received. Faculty noted that residents were not only completing the assigned cases but proactively requesting more. Program leadership observed that residents felt more organized as a result — and that DDx encouraged productive self-directed learning habits during a time of high transition.
Five residency-level emergency medicine DDx cases were available for residents to workthrough.



The results
Residents showed meaningful improvements across all measured clinical competencies. Confidence in ordering medications improved by 48.75%, confidence in interpreting results improved by 37.86%, and confidence in identifying appropriate admission settings improved by 27.50%. Residents reached 100% agreement on multiple key experience metrics — including that DDx improved their confidence in clinical reasoning, that the cases were realistic and relevant, and that they would use the platform for self-guided learning outside of assigned cases.
Testimonials
The UC Irvine Emergency Medicine Residency pilot demonstrated that DDx is more than a learning tool — it is a primer for clinical performance. By embedding it into intern orientation, faculty offered residents a way to practice critical thinking, identify knowledge gaps, and build clinical confidence before ever stepping into the ED. With strong resident engagement and meaningful faculty feedback, DDx proved to be a scalable and effective enhancement to graduate medical education.
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